Procainamide/Amiodarone Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Both procainamide and amiodarone can affect your heart rhythm.

What might happen:

These medicines may be used together to help keep your heart rhythm stable. However, there is also a chance that the combination may increase your risk for an irregular heartbeat, which may be very serious.

What you should do about this interaction:

Make sure your cardiologist (heart doctor) knows you are taking these medicines together. Also make sure your doctor knows all the other medicines you are taking. Let your doctor know right away if you notice an irregular heartbeat or have any dizziness or fainting episodes. Your doctor may want to perform tests of your heart function, check blood levels of your medicine, and may want to adjust the dose of one or both medicines.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.