Daprodustat; Roxadustat; Vadadustat/Lenalidomide Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
It is unknown what increases this risk.
What might happen:
You may be at a higher risk for blood clots in your arteries, veins and lungs, heart attack, and stroke when taking these two medicines together.
What you should do about this interaction:
Make sure healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to change your medicines.Seek medical care immediately if you experience chest pain; shortness of breath; pain in your arms, neck, jaw or back; swelling, pain, or tenderness in your legs; sudden numbness or weakness, especially on one side of the body; headache or confusion; or problems with vision, speech, or balance.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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- 2.Jesduvroq (daprodustat) US Prescribing Information. GlaxoSmithKline Feb, 2023.
- 3.Evrenzo (roxadustat) UK summary of product characteristics. Atellas Pharma Europe B.V. November, 2021.
- 4.Vafseo (vadadustat) Australian prescribing information. Akebia Therapeutics, Inc. October, 2023.
- 5.Vafseo (vadadustat) UK Summary of Product Characteristics. Akebia Europe Limited May, 2023.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.