Skip to content

    Read user comments about the side effects, benefits, and effectiveness of Synvisc-One intra-articular.

    Overall User Ratings

    266 Total User Reviews

    User Reviews

    1-5 of 243 Next»
    Condition: Osteoarthritis of the Knee
    7/31/2020 4:01:03 PM

    Reviewer: Jtevis, 55-64 Female on Treatment for 1 to 6 months (Patient)

    Effectiveness

    Current Rating: 1

    Ease of Use

    Current Rating: 1

    Satisfaction

    Current Rating: 1

    Comment:
    I suffered a rare side effect to this drug and I will never use it again. I went from painful knees to horrific pain from my hip to ankle in both legs. I lost my ability to walk and had chills, fever, headaches and nothing would help. The doctor prescribed a prednisone pack and it is helping but I still have a long way to go and not sure I will ever be the same. Almost 3 weeks later and I stil ... Show Full Comment

    Condition: Osteoarthritis of the Knee
    7/26/2020 7:01:03 AM

    Reviewer: Honda Mike, 55-64 on Treatment for 10 years or more (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 5

    Comment:
    At 56 years old I run 8 mikes every day and 26 on Saturday. My knees hurt and I thought I would never run again. Three runners on my team had this injection and said it works. I had it 8 years ago. Immediate relief and still today I run pain free.

    Condition: Osteoarthritis of the Knee
    1/18/2020 6:34:20 PM

    Reviewer: sonia, 55-64 Female on Treatment for 1 to 6 months (Patient)

    Effectiveness

    Current Rating: 1

    Ease of Use

    Current Rating: 1

    Satisfaction

    Current Rating: 1

    Comment:
    I had the 2nd of 3 injections in my knee the Monday before Thanksgiving 2019 and by Thanksgiving I could no longer walk. As of 1/18/2020 I still can't walk!! This Drug should be off the market before it hurts someone else!! There are other injections that work that don't have issues like this one does!!

    Condition: Osteoarthritis of the Knee
    1/6/2020 2:52:09 AM

    Reviewer: Anonymous , 35-44 Female on Treatment for 2 to less than 5 years (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 5

    Comment:
    Had my first synviscone shot over two years ago and lost about 15 pounds over a year ago. Feel like my knee is brand new. I was in extreme pain 24/7 and my ortho recommended we try this before knee replacement. It’s been a total game changer for me! I recommend having an ortho do the shot to avoid potential issues with improper injection placement. It was less painful than a cortisone shot. It too ... Show Full Comment

    Condition: Osteoarthritis of the Knee
    11/18/2019 5:50:37 PM

    Reviewer: 65-74 Female on Treatment for 5 to less than 10 years (Patient)

    Effectiveness

    Current Rating: 4

    Ease of Use

    Current Rating: 3

    Satisfaction

    Current Rating: 4

    Comment:

    1-5 of 243 Next»

    Ask the pharmacist

    Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
    See the Ask the Pharmacist event schedule.

    Ask a Question

    Popular Slideshows & Tools on WebMD

    disciplining a boy
    Types, symptoms, causes.
    fruit drinks
    Eat these to think better.
    bald woman smelling flowers
    Complementary therapies to ease symptoms.
    embarrassed woman
    Do you feel guilty after eating?
    diabetes highlighted
    4 early warning signs.
    birth control pills
    Which kind is right for you?
    Remember your finger
    Are you getting more forgetful?
    sticky notes on face
    10 tips to clear your brain fog.
    Close up of eye
    12 reasons you're distracted.
    Trainer demonstrating exercise for RA
    Exercises for your joints.
    Senior woman using diabetes test kit
    Each one takes 10 minutes or less.
    woman having a good day
    Revitalize your life.

    WebMD the app

    Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

    Find Out More
    IMPORTANT: About This Section and Other User-Generated Content on WebMD

    The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

    Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.