Reviewer: harley1000, 55-64 Male on Treatment for less than 1 month (Patient)

Comment:
Adverse effect of Cycloset, taken with Janumet and Amaryl .8mg of Cycloset x 4 per day. started at 1/day/for first week, worked up to 2 per day second week.. Could not continue ramping up to recommended dose of 4 pills per day. Experienced chest pains, fatigue, upset stomach, vomiting. Discontinued taking pills. Felt great. Spoke to my endocrinologist. She recommended "sticking it out a ... Show Full Comment

Comment:
Adverse effect of Cycloset, taken with Janumet and Amaryl .8mg of Cycloset x 4 per day. started at 1/day/for first week, worked up to 2 per day second week.. Could not continue ramping up to recommended dose of 4 pills per day. Experienced chest pains, fatigue, upset stomach, vomiting. Discontinued taking pills. Felt great. Spoke to my endocrinologist. She recommended "sticking it out again" to reach the recommended dosage levels of 4 pills. Tried it again in 2 weeks, same results, but, incredibly, after taking the drug, my glucose levels actually increased following the 2 hour administration. Woke up at 700 am, took 2 pills, took reading = 132. Had black coffee, 1 egg, 1 piece cheese. Reading after 2 hours = 198, with no carbs. Reading stayed high into the night. This effect was repeated for several days. Tried same meal after discontinuing Cycloset. Initial reading = 135, post meal= 141. This effect was repeatable during the 2 week period in which I was taking the drug. Perhaps if I made it to the recommended dose of 4 x .82mg, it would work, but getting there is not worth the suffering, and there is no guarantee it would abate at some point. Finally gave up completely. Hope this helps I was better off not taking the Cycloset.
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Reviewer: missdee77, 35-44 Female on Treatment for 6 months to less than 1 year (Patient)

Comment:
I had the same experience as Cheryl, this medicine gave me flu- like symptoms, really horrible! My doctor wanted me to give it time, I gave it almost a year. Awful pain in my stomach, constant nausea, & lethargic, I refused to take it anymore & was switched to Amryl, which is working great. I really think this medicine Cycloset is headed toward the recall list in the very near future. TERR ... Show Full Comment

Comment:
I had the same experience as Cheryl, this medicine gave me flu- like symptoms, really horrible! My doctor wanted me to give it time, I gave it almost a year. Awful pain in my stomach, constant nausea, & lethargic, I refused to take it anymore & was switched to Amryl, which is working great. I really think this medicine Cycloset is headed toward the recall list in the very near future. TERRIBLE!
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Reviewer: Cheryl, in AZ., 45-54 on Treatment for 1 to 6 months (Patient)

Comment:
I take byetta, and metformin for my type 2 diabetes, my fasting readings are between 105 -120 my last A1C reading was 7.1 so my Dr. perscribed Cycloset. It is horrible! I have never felt so sick in all my life! He wanted me to work my way up to taking 6 pills a day. I can barely handle 2. I have tried to take 3 but I can't even function. I am always throwing up, I guess this is how you are ... Show Full Comment

Comment:
I take byetta, and metformin for my type 2 diabetes, my fasting readings are between 105 -120 my last A1C reading was 7.1 so my Dr. perscribed Cycloset. It is horrible! I have never felt so sick in all my life! He wanted me to work my way up to taking 6 pills a day. I can barely handle 2. I have tried to take 3 but I can't even function. I am always throwing up, I guess this is how you are supposed to "lose weight" on this pill. It hasn't made a difference in my daily blood suga readings, which were good to excellent to begin with. I don't recommend this drug for anyone. I don't know how much longer I will be taking it, it has not benefitted me at all.
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Reviewer: 45-54 Male on Treatment for 1 to 6 months (Patient)

Comment:
Ive been on Cycloset for about 3 month's now after being on Metformin Ext Release. My cycloset dosage is ,125. I was on Metformin for about 4 years, read about cycloset's effect as far as having dopamine help with the blood sugar levels, so I asked my PCP (primary care phys)that I wanted to try cycloset. My recent lab results were considered normal with my a1c at 6.3. I'm considere ... Show Full Comment

Comment:
Ive been on Cycloset for about 3 month's now after being on Metformin Ext Release. My cycloset dosage is ,125. I was on Metformin for about 4 years, read about cycloset's effect as far as having dopamine help with the blood sugar levels, so I asked my PCP (primary care phys)that I wanted to try cycloset. My recent lab results were considered normal with my a1c at 6.3. I'm considered pre-diabetic, and have been for the last 3 years. Ironic that my Doctor of Naturopathic Medicine diagnosed it, and saw that my vitamin D levels were low. When I last saw my PCP, he recommended that I track my blood sugar mg/dL, and the last 10 ave for fasting was 113.2mg/dL, and post meal last 10 readings were ave at 123.5mg/dL. I have not had noticeable adverse symptoms using cycloset. I plan to keep using it through 2012, and reassess for 2013. I am 53 yrs old, 6ft 2in, and weight in at 296lbs. I bodybuild (weightlifting) as a hobby, 2+ hrs 5days/week, and 45min-1hr cardio.
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Reviewer: lgordon, 35-44 Female on Treatment for 1 to 6 months (Patient)

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