Reviewer: ladyloulee, 25-34 Female on Treatment for 1 to less than 2 years (Patient)

Comment:
An absolute miracle drug in relation to my depression. I have been on anti depressants for over 15 years and have never felt this "alive" in my entire life. Currently it is prescribed as an adjunt with Celexa

Comment:
An absolute miracle drug in relation to my depression. I have been on anti depressants for over 15 years and have never felt this "alive" in my entire life. Currently it is prescribed as an adjunt with Celexa
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Reviewer: Nell, 35-44 Female on Treatment for 6 months to less than 1 year (Patient)

Comment:
It does what it's supposed to do and very well, but it's tricky, especially for me, a woman. If you read Dr. Atkins, he's pretty clear that folate behaves like estrogen and I definitely felt that because I didn't ramp up at first. Also, read up on the folic acid cycle and the other nutrients involved such as B12, Vitamin C and read about Homocysteine and heme. These are all rela ... Show Full Comment

Comment:
It does what it's supposed to do and very well, but it's tricky, especially for me, a woman. If you read Dr. Atkins, he's pretty clear that folate behaves like estrogen and I definitely felt that because I didn't ramp up at first. Also, read up on the folic acid cycle and the other nutrients involved such as B12, Vitamin C and read about Homocysteine and heme. These are all related topics. You shouldn't just take folic acid alone. Nothing in your body works alone. That's the mistake I made at first. I felt like I was having the worst PMS day of my life from just one megadose. You have to work up to it. The FDA does have a too-low RDA for it, though, so everyone's deficient in it. Find some videos by Dr. Bruce Ames (a biochemist not MD) to get some ideas about how deficient people are in general in many vitamins and also for an explanation about why he believes and I believe that folic acid deficiency is "like being irradiated." Just be careful when you start out, and at least take a multivitamin with it.
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Reviewer: LARL, 55-64 Female on Treatment for 6 months to less than 1 year (Patient)

Comment:
Prescribed for me to 'boost' effect of antidepressant. Definitely helps me feel better with no side effects. Taking 15-mg caplet once per day.

Comment:
Prescribed for me to 'boost' effect of antidepressant. Definitely helps me feel better with no side effects. Taking 15-mg caplet once per day.
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Reviewer: Alicia, 45-54 Female on Treatment for 1 to 6 months (Patient)

Comment:
I felt noticeably better at first... less anxious, happy, interacting and alert. I went from that to wanting to close myself in a room and be alone. My anxiety was back and along with that were major muscle and joint aches. I looked up side effects on mthfr.net and this reaction was one of three typical responses to taking methy-folate.Why does methylfolate create such an amazing week and then cre ... Show Full Comment

Comment:
I felt noticeably better at first... less anxious, happy, interacting and alert. I went from that to wanting to close myself in a room and be alone. My anxiety was back and along with that were major muscle and joint aches. I looked up side effects on mthfr.net and this reaction was one of three typical responses to taking methy-folate.Why does methylfolate create such an amazing week and then create such severe side effects so soon after? According to Dr. Lynch, it has to do with methylation, pre-existing inflammation and possibly genetic mutations. He doesn't necessarily recommend stopping the drug but tapering up and taking other supplements with it. Doing that helped me.
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