Reviewer: Simon, 75 or over on Treatment for less than 1 month

Comment:
Had a nearly immediate effect of redness, irritation and burning all over the applied zone on my face and neck. Was so severe that I stopped after 7 days. However within a further 10 days and massive peeling of decayed skin, my face was restored to a normal condition. A dermatologist later stated that she would recommend application only every other day. Conclusion was that the discomfort was wort ... Show Full Comment

Comment:
Had a nearly immediate effect of redness, irritation and burning all over the applied zone on my face and neck. Was so severe that I stopped after 7 days. However within a further 10 days and massive peeling of decayed skin, my face was restored to a normal condition. A dermatologist later stated that she would recommend application only every other day. Conclusion was that the discomfort was worth it as my condition has improved out of all recognition.
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Reviewer: MLaughlin, 55-64 on Treatment for less than 1 month (Patient)

Comment:
A piece of advice. If you finished with the application stage of this medication and are using an ointment such as hydrocortisone ointment or Vaseline, if you start to feel excessive burning and itching, sometimes coming on fairly quickly, wash off your current ointment with a gentle soap and rinse thoroughly. Then reapply the ointment. Chances are, you are sweating underneath the ointment and it ... Show Full Comment

Comment:
A piece of advice. If you finished with the application stage of this medication and are using an ointment such as hydrocortisone ointment or Vaseline, if you start to feel excessive burning and itching, sometimes coming on fairly quickly, wash off your current ointment with a gentle soap and rinse thoroughly. Then reapply the ointment. Chances are, you are sweating underneath the ointment and it is pushing into your inflamed skin. You are literally pouring salt on your wounds. It will burn for a moment, and then the inflammation will calm down some, probably to tolerable levels.
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Reviewer: mkk, 55-64 Female on Treatment for less than 1 month (Patient)

Comment:
Every time I use Efudex, even on a small area, I feel mildly nauseated and the skin on my hands gets painfully dry. Doctors keep telling me that this isn't caused by the Efudex, and I keep believing them. I use it again, and by day 10 I'm nauseated and the skin on my hands is once again like sandpaper, dry and cracked.

Comment:
Every time I use Efudex, even on a small area, I feel mildly nauseated and the skin on my hands gets painfully dry. Doctors keep telling me that this isn't caused by the Efudex, and I keep believing them. I use it again, and by day 10 I'm nauseated and the skin on my hands is once again like sandpaper, dry and cracked.
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Reviewer: 55-64 Female on Treatment for less than 1 month (Patient)

Comment:
I read a lot of horror stories online which was a mistake. I found this treatment to be nothing as harsh as others have related here. I did the upper lip for 10 days forehead and nose for 14. I have less wrinkles and less precancerous cells on my face. It was easy to use...just dont go online and read the horror stories

Comment:
I read a lot of horror stories online which was a mistake. I found this treatment to be nothing as harsh as others have related here. I did the upper lip for 10 days forehead and nose for 14. I have less wrinkles and less precancerous cells on my face. It was easy to use...just dont go online and read the horror stories
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Reviewer: no pain no gain ??????, 75 or over on Treatment for 1 to 6 months

Comment:
I could not go thru this again, it's so painful and the itching never lets up, the itching is the worst, my head feels like it's on fire, can't sleep, the only temporary relief is to put a piece of towelling soaked in cold water and squeeze out the excess water, gives relief for 30 to 60 minutes, then the towelling feels so hot almost like it would catch fire, do not do this until yo ... Show Full Comment

Comment:
I could not go thru this again, it's so painful and the itching never lets up, the itching is the worst, my head feels like it's on fire, can't sleep, the only temporary relief is to put a piece of towelling soaked in cold water and squeeze out the excess water, gives relief for 30 to 60 minutes, then the towelling feels so hot almost like it would catch fire, do not do this until you have removed the excess Efudix this is after the full cycle, as the cold water has a very painful reaction, warm to fairly hot water is okay, I did the full 28 day treatment.I consider myself to be able handle pain fairly well, having had 2 bad accidents, but these were nothing compared to this, good luck what ever your decision. I notice here in Australia the product is called slightly different Efudix as opposed to Efudex but it looks like the symptoms are at least similar.nh
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