Skip to content

    Read user comments about the side effects, benefits, and effectiveness of Santyl topical.

    Overall User Ratings

    38 Total User Reviews

    User Reviews

    1-5 of 22 Next»
    Condition: Skin Ulcer
    4/18/2018 2:50:20 PM

    Reviewer: Pleased with Santyl, 65-74 on Treatment for less than 1 month (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 5

    Comment:
    My husband has an diabetic ulcer on the bottom of his toe. This has been since January. Started to heal nicely but then stopped and became infected. His podiatrist reopened the ulcer and started to apply Santyl. He did not experience any burning, pain or redness. It is now all most healed completely and its only been one week. I never leave reviews but felt to do so. I'm very pleased with the ... Show Full Comment

    Condition: Skin Ulcer
    5/9/2016 4:35:18 AM

    Reviewer: JSG, 55-64 on Treatment for less than 1 month (Patient)

    Effectiveness

    Current Rating: 1

    Ease of Use

    Current Rating: 1

    Satisfaction

    Current Rating: 1

    Comment:
    Entering a 2nd week without sleep since attempting to use Santyl with Bandages to treat a fairly severe case of leg skin ulcers. As the previous gentlemen indicated, the degree of pain I have experienced using this Ointment most closely compares to that of 2nd & 3rd Degree Burns received in a Fire Explosion.

    Condition: Skin Ulcer
    3/14/2016 3:19:15 PM

    Reviewer: Happy, 45-54 Female on Treatment for less than 1 month (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 5

    Satisfaction

    Current Rating: 5

    Comment:
    My Doctor prescribe this ointment, because my wound was not healing. Been using it for almost three weeks now and the wound is healing nicely. I did not experience any burning, just redness and that gradually went away.

    Condition: Skin Ulcer
    10/18/2015 3:54:42 PM

    Reviewer: TheGoodBubba, 65-74 Male on Treatment for 1 to 6 months (Patient)

    Effectiveness

    Current Rating: 4

    Ease of Use

    Current Rating: 1

    Satisfaction

    Current Rating: 1

    Comment:
    This works but the pain and burning in the wound is unreal. Can't sleep at all from pain, oxycodone 30mg doesn't touch the pain. I have a pressure wound on my ankle. The pain on the nerves is just unbearable. The pain is so intense that it radiates out all over my ankle and up my leg. I got 8mg dilaudid and still the pain is there. If you love pain this is for you. When I put another dres ... Show Full Comment

    Condition: Skin Ulcer
    10/10/2015 1:55:28 PM

    Reviewer: TheGoodBubba, 65-74 Male (Patient)

    Effectiveness

    Current Rating: 5

    Ease of Use

    Current Rating: 1

    Satisfaction

    Current Rating: 3

    Comment:
    Santyl works to remove dead tissue very well but it burns and hurts like hell right inside the wound. I could not sleep the pain was so bad so at night I replace the Santyl with Solosite Gel so I can sleep. No doubt about it, it's the Santyl causing the pain because with Solosite the pain drops by 90%. The MedHoney will also burn like hell right inside the wound.

    1-5 of 22 Next»

    Ask the pharmacist

    Questions about medications? Get expert answers by video or live chat about allergies, pregnancy, sleep, and more.
    See the Ask the Pharmacist event schedule.

    Ask a Question

    Popular Slideshows & Tools on WebMD

    disciplining a boy
    Types, symptoms, causes.
    fruit drinks
    Eat these to think better.
    bald woman smelling flowers
    Complementary therapies to ease symptoms.
    embarrassed woman
    Do you feel guilty after eating?
    diabetes highlighted
    4 early warning signs.
    birth control pills
    Which kind is right for you?
    Remember your finger
    Are you getting more forgetful?
    sticky notes on face
    10 tips to clear your brain fog.
    Close up of eye
    12 reasons you're distracted.
    Trainer demonstrating exercise for RA
    Exercises for your joints.
    Senior woman using diabetes test kit
    Each one takes 10 minutes or less.
    woman having a good day
    Revitalize your life.

    WebMD the app

    Get trusted health information. Whenever. Wherever... with your iPhone, iPad or Android.

    Find Out More
    IMPORTANT: About This Section and Other User-Generated Content on WebMD

    The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

    Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.