Who should not take Tofacitinib Tablet?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:

Conditions:

  • a patient who is producing milk and breastfeeding
  • disorder of lymphoid tissue after transplant
  • malignant lymphoma
  • cancer or malignancy
  • liver problems
  • a decreased number of lymphocytes in the blood
  • anemia
  • opportunistic fungal infection
  • inactive tuberculosis
  • tobacco smoking
  • a blood clot
  • lung tissue problem
  • hardening of the arteries due to plaque buildup
  • an increased risk of developing an uncommon viral infection called an opportunistic infection
  • kidney disease with likely reduction in kidney function
  • diverticulitis
  • low levels of a type of white blood cell called neutrophils
  • a bad infection
  • shingles
  • active tuberculosis
  • Child-Pugh class B liver impairment
  • chronic kidney disease stage 5 (failure)
  • chronic kidney disease stage 4 (severe)
  • chronic kidney disease stage 3B (moderate)
  • chronic kidney disease stage 3A (moderate)

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.