Labetalol/Diltiazem; Verapamil Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Very Serious. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, the effects of one or both medicines may increase. Heart problems and high doses of your beta-blocker may increase the chance for harmful effects. Using additional heart medicines may also lead to harmful effects.
What might happen:
You may experience an increase in side effects from one or both medicines, including low blood pressure, slow heart rate, heart block, and heart failure.
What you should do about this interaction:
Let your healthcare professionals (e.g., doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to change your medicines. If you experience a slow or irregular heartbeat, chest pain, shortness of breath, dizziness or lightheadedness, or confusion, contact your doctor right away.Your healthcare professionals may already be aware of this drug interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Labetalol Hydrochloride US prescribing information. Alvogen, Inc. April, 2024.
- 2.Labetalol Hydrochloride Injection US prescribing information. Hikma Pharmaceuticals USA Inc. June, 2023.
- 3.Covera-HS (verapamil hydrochloride) US prescribing information. G.D. Searle LLC September, 2017.
- 4.Cardizem LA (diltiazem hcl extended release tablets) US prescribing information. Abbott Pharmaceuticals, Inc. November, 2016.
Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.